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菌状乳头受舌神经的味觉神经纤维支配,与中枢神经系统共同形成味觉。临床上舌前部味觉病变往往有两种,一种属周围性的,是因舌神经受损伤或者菌状乳头本身病变,往往表现为菌状乳头萎缩或消失;另一种属中枢性的,是因味觉中枢病变而使味觉改变,但菌状乳头并无改变。我们在评价舌前部味觉功能时,将液池内的菌状乳头染色,进行形态学观察和定量检查,将检测味觉功能和菌状乳头的定量检查结合起来,能够更全面、客观、准确地评价舌前部的味觉功能,有利鉴别味觉病变的程度和属于周围性的还是中枢性的,特别对舌神经损伤和修复后的味觉功能以及菌状乳头的变化进行动态研究,更具有临床意义[2]。
本研究为美国国立卫生研究院和江苏省教委自然科学基金资助 作者单位:210029 南京医科大学口腔医院(陈宁、杨筱荣);美国北卡罗来纳大学牙科学院(John R. Zuniga)
参考文献
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